Central Dogma
Definition of Gene
Proof that DNA |
Proof that DNA is Genetic MaterialGriffithWhen he added dead, virulent pneumonia bacteria to a mouse, it lived; but if he added dead virulent bacteria to live non-virulent bacteria some mice died. He termed the material that changed the non-virulent bacteria to virulent the transforming principle.
Avery, MacLeod and McCartyThey used biochemical purification of cellular fractions to determine that DNA and not RNA or protein was the transforming principle.Transformation - the alteration of phenotype by the addition of foreign DNA
Hershey and Chase The "Blender Experiment"They knew that:
Protein - has S but not P
Copyright © 1998. Phillip McClean |