The Fillmore Lab studies how energy metabolism contributes to metabolic diseases such as type II diabetes and cardiovascular disease, particularly in heart and skeletal muscle. To develop strategies to treat these diseases, the Fillmore Lab works to understand the regulation of metabolism and its role in disease.

Research Objectives

1. Understand the mechanisms by which energy metabolism regulates insulin resistance
2. Elucidate the mechanisms by which of fatty acid signaling regulates cardiac hypertrophy and function.
3. Explore the mechanisms involved in the crosstalk between the heart and the metabolism of systemic tissues

Publications

Fillmore Lab funding

ND-EPSCOR

Contact Us

Natasha Fillmore

Phone
701.231.1876

Physical/delivery address
1401 Albrecht Boulevard, Fargo, ND 58102

Mailing address
NDSU Dept. 2660 / PO Box 6050 / Fargo, ND 58108-6050

Campus Map

Fillmore Lab news

Fillmore N, Hou V, Sun J, Springer D, Murphy E. Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2. PLoS One. 2022 Mar 8;17(3):e0265007.