Mara Hirchert

Research Specialist (Molecular Biology)

Staff

Animal Sciences

headshot of Mara Hirchert

Areas of Study & Research

During my graduate program as a PhD student, I studied nutrigenomics, which is the study of the effects of nutrients on the DNA/genome. On my PhD thesis I investigated the protective effects of the Amazon fruit Piquiá on DNA damage using rats as animal model. During my postdoc fellowship, I studied the effects of the vitamin B6 maternal supplementation and restriction on offspring DNA damage and gene expression.
I am now a Research Specialist at the Genetics Laboratory in the Animal Sciences Department and I participate in animal nutrition experiments with focus on the effects of maternal nutrition on offspring. I perform all the assay within the Genetics Laboratory such as, but not limited to, real time PCR, biochemistry assays and mitochondria function using the XFe24 instrument.

Education

  • PhD in Toxicology
  • Master's in Clinical Pathology
  • Bachelor's degree in Biomedical Sciences

Publications

1.Chequer, Farah MD; Venancio, Vinicius Paula; Almeida, Mara Ribeiro*; Aissa, Alexandre Ferro; Bianchi, Maria de Lourdes Pires; Antunes, Lusânia Maria Greggi.
Erythrosine B and quinoline yellow dyes regulate DNA repair gene expression in Human HepG2 cells. Toxicology and Industrial Health, v. 33, p. 765-774, 2017.

2. Almeida, Mara Ribeiro*; Mabasa, Lawrence; Crane, Courtney; Park, Chung S; Venâncio, Vinícius Paula; Bianchi, Maria Lourdes Pires; Antunes, Lusânia Maria Greggi.
Maternal vitamin B6 deficient or supplemented diets on expression of genes related to GABAergic, serotonergic, or glutamatergic pathways in hippocampus of rat dams and their offspring. Revista: Molecular Nutrition and Food Research, v. 60, p. 1615-1624, 2016.

3. Venâncio, Vinicius Paula; Marques, Marcella Camargo; Almeida, Mara Ribeiro*; Mariutti, Lilian Regina Barros; Souza, Vanessa Cristina de Oliveira; Barbosa Jr, Fernando; Bianchi, Maria Lourdes Pires; Marzocchi-Machado, Cleni Mara; Mercadante, Adriana Zerlotti; Antunes, Lusânia Maria Greggi.
Chrysobalanus icaco L. fruits inhibit NADPH oxidase complex and protect DNA against doxorubicin-induced damage in vivo. Journal of Toxicology and Environmental Health, Part A, v. 79(20), p. 885-893

4. Almeida, Mara Ribeiro*; Venâncio, Vinícius de Paula; Aissa, Alexandre Ferro; Darin, Joana Darc Castania; Bianchi, Maria Lourdes; Antuens, Lusânia Maria Greggi
Effects of maternal vitamin B6 deficiency and over-supplementation on DNA damage and oxidative stress in rat dams and their offspring Food and Chemical Toxicology. Food and Chemical Toxicology. , v.80, p.201 - 205, 2015.

5. Konta, Eliziani Mieko; Almeida, Mara Ribeiro*; Amaral, Cátia Lira do; Darin, Joana D'Arc Castania; Rosso, Veridiana V.; Mercadante, Adriana Zerlotti; Antunes, Lusânia Maria Greggi; Bianchi, Maria Lourdes Pires
Evaluation of the Antihypertensive Properties of Yellow Passion Fruit Pulp (Passiflora edulis Sims f. flavicarpa Deg.) in Spontaneously Hypertensive Rats. Phytotherapy Research (Online). , v.28, p.28 - 32, 2014.

6. Hernandes, Lívia Cristina; Aissa, Alexandre Ferro; de Almeida, Mara Ribeiro*; Darin, Joana Darc Castania; Rodrigues, Eliseu; Batista, Bruno Lemos; Júnior, Fernando Barbosa; Mercadante, Adriana Zerlotti; Bianchi, Maria Lourdes Pires; Antunes, Lusânia Maria Greggi
In vivo assessment of the cytotoxic, genotoxic and antigenotoxic potential of maná-cubiu (Solanum sessiliflorum Dunal) fruit. Food Research International. , v.62, p.121 - 127, 2014.

7. Serpeloni, Juliana Mara; Almeida, Mara Ribeiro*, Mercadante, Adriana Zerlotti; Bianchi, Maria Lourdes Pires; Antunes, Lusânia Maria Greggi.
Effects of lutein and chlorophyll b on GSH depletion and DNA damage induced by cisplatin in vivo. Human & Experimental Toxicology. , v.32, p.828 - 836, 2013.

8. Almeida, Mara Ribeiro*; Aissa, Alexandre Ferro; Gomes, Tarsila Daysy Ursula Hermogenes; Darin, Joana D'Arc Castania; Chisté, Renan Campos; Mercadante, Adriana Zerlotti; Antunes, Lusânia Maria Greggi; Bianchi, Maria Lourdes Pires
In vivo Genotoxicity and Oxidative Stress Evaluation of an Ethanolic Extract from Piquiá (Caryocar villosum) Pulp. Journal of Medicinal Food. , v.16, p.268 - 271, 2013.

9. Aissa, Alexandre Ferro; Gomes, Tarsila Daysy Ursula Hermogenes; Almeida, Mara Ribeiro*; Hernandes, Lívia Cristina; Darin, Joana Darc Castania; Bianchi, Maria Lourdes Pires; Antunes, Lusânia Maria Greggi
Methionine concentration in the diet has a tissue-specific effect on chromosomal stability in female mice. Food and Chemical Toxicology. , v.62, p.456 - 462, 2013.

10. Pereira, Bruno Cesar; Pauli, José Rodrigo; Antunes, Lusânia Maria Greggi; de Freitas; Ellen Cristini; de Almeida, Mara Ribeiro*; de Paula Venâncio, Vinícius; Ropelle, Eduardo Rochete; de Souza, Claudio Teodoro; Cintra, Dennys Esper; Papoti, Marcelo; da Silva, Adelino Sanchez
Overtraining is associated with DNA damage in blood and skeletal muscle cells of Swiss mice. BMC Physiology (Online). , v.13, p.11 - , 2013.